Endoribonuclease type II toxin–antitoxin systems: functional or selfish?

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چکیده

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Endoribonuclease type II toxin-antitoxin systems: functional or selfish?

Most bacterial genomes have multiple type II toxin-antitoxin systems (TAs) that encode two proteins which are referred to as a toxin and an antitoxin. Toxins inhibit a cellular process, while the interaction of the antitoxin with the toxin attenuates the toxin's activity. Endoribonuclease-encoding TAs cleave RNA in a sequence-dependent fashion, resulting in translational inhibition. To account ...

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Commentary: What Is the Link between Stringent Response, Endoribonuclease Encoding Type II Toxin-Antitoxin Systems and Persistence?

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ژورنال

عنوان ژورنال: Microbiology

سال: 2017

ISSN: 1350-0872,1465-2080

DOI: 10.1099/mic.0.000487